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Nigeria has adopted unprecedented measures to control the rapid spread of COVID-19 pandemic in the country. Citizens’ adherence to control measures is affected by their knowledge, beliefs, and Practices towards COVID-19. This study investigated the knowledge, beliefs and practices of the Covid-19 pandemic among Nigerians. The study adopted a cross-sectional web-based survey. The population of the study comprised Nigeria population of 200,000000 and a sample of 384 was drawn from the population. Data were analysed using descriptive and inferential statistics at 0.05 level of significance. The results of the study revealed that the respondents’ knowledge of the pandemic was very high and that the respondents do not have negative beliefs about Covid-19 pandemic. The results further revealed that the respondents were observing most of the Covid-19 rules and protocols. The study concluded that government at all levels should engage in continuous sensitization of the masses targeting both urban and rural communities in order to achieve higher knowledge and maintain safe practices.