The study examined information literacy skills as a correlate to the use of library resources among Polytechnic students in Delta State Nigeria. The specific objectives of the study aimed at determining the level of information literacy skills, ascertaining the extent to which the students information literacy skills affect their use of library resources, and finding out the relationship between information literacy skills and library resources among Polytechnic students in Delta State Nigeria. Two research questions were postulated, and one hypothesis tested for the study. The study adopted the descriptive survey research design. The Population of the study was 16,050 respondents drawn from the three polytechnics in Delta State Nigeria. The Sample size was 642 respondents. The cluster and random sampling were the sampling techniques used. The instrument used for data collection was the questionnaire; the inferential and descriptive statistics were used to analyze data collected. The findings indicated that the level of information literacy skills possessed by Polytechnic students in Delta State Nigeria is low. Also, the extent to which their information literacy skills affect their use of library resources is low. It was concluded that a significant relationship exists between information literacy skills and Polytechnic students use of library resources. Based on the findings, the researcher recommended that collaborate efforts should be made between the management of Polytechnics, librarians and other teaching staff geared towards developing students information literacy skills for sustainable independent learning.