Nutrition and Health Sciences, Department of


Document Type


Date of this Version



Published in Gastroenterology Clinics of North America 46 (2017), pp 783–795.

doi 10.1016/j.gtc.2017.08.004


Copyright © 2017 Elsevier Inc. Used by permission.


Inflammatory bowel disease risk factors include poor diet, and corresponding low intake of dietary fiber, specifically prebiotics, which is fermented by the gut microbiota. Dietary fibers, many of which are potential prebiotics, have hundreds to thousands of unique chemical structures that may promote bacteria or bacterial groups to provide beneficial health effects. In vitro and in vivo animal models provide some support for the use of prebiotics for inflammatory bowel disease through inflammation reduction. Studies using prebiotics in patients with inflammatory bowel disease are limited and focus on only a select few prebiotic substances.

Keywords: Inflammatory bowel disease, Ulcerative colitis, Crohn disease, Prebiotics, Fiber