USDA National Wildlife Research Center Symposia



Mark P. Bradley

Date of this Version

October 1993


Contraception in wildlife management. APHIS Technical Bulletin No. 1853. USDA, Animal and Plant Health Inspection Service, Washington, D.C., USA.


This paper describes the strategies being employed in the development of an immunocontraceptive vaccine using sperm antigens, to control fox populations in Australia. It is proposed that such a vaccine will be delivered orally in a bait, thereby ultimately stimulating a mucosal immune response within the female reproductive tract. The eventual success in producing such a vaccine requires the identification of game antigens that cause immunological infertility, a detailed understanding of the reproductive immunology of foxes and the selection of the most effective form of antigen delivery system.