Research Papers in Physics and Astronomy


Date of this Version

August 1993


NASA Technical Paper 3351


Track theory is combined with a realistic model of a heavy ion beam to study the effects of nuclear fragmentation on cell survival and biological effectiveness . The effects of secondary reaction products are studied as a function of depth in a water column. Good agreement is found with experimental results for the survival of human T-1 cells exposed to monoenergetic carbon, neon, and argon beams under aerobic and hypoxic conditions. The present calculation, which includes the effect of target fragmentation, is a significant improvement over an earlier calculation because of the use of a vastly improved beam model with no change in the track theory or cellular response parameters.

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