Date of this Version
Parasitology Today, vol. 10, no 8, 1994
Roberts et al. cited work from this laboratory, which to them suggested that '... immunity can develop after relatively few (certainly less than 10) episodes of clinical malaria'. Although this statement appears largely true to the cited work, it is important to point out that the supporting evidence applied to adults but not to children. In our studies of people with limited histories of exposure to endemic malaria, children remained susceptible to frequent and high-grade parasitemia after several years, whereas adults apparently developed protection. These findings were confirmed with additional studies.