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"Brain Tumor in a Dish: Glioma/Astrocyte Co-Cultures as a Model for In Vitro Studies," Erin Eickman, Christina Wilson, and Srivatsan Kidambi, Department of Chemical and Biomolecular Engineering, University of Nebraska-Lincoln. Spring 2016 Research Fair poster.
This study seeks to engineer an in vitro co-culture model to elucidate the role of glioma-astrocyte interactions on molecular changes in the tumor microenvironment. The use of patterned co-cultures created with polyelectrolyte multilayers and micromolding in capillaries will allow tthe investigation of cell-cell communication. This study will lead to better understanding of the role of healthy cells in cancer progression and potential treatment options.