UCARE: Undergraduate Creative Activities & Research Experiences


Date of this Version

Spring 4-15-2016

Document Type



UCARE presentation, University of Nebraska-Lincoln Research Fair, April 2016, Lincoln, NE.


Copyright © 2016 Avi Knecht, Adam Caprez, & Istvan Ladunga


When gene regulation of the cell cycle malfunctions, it frequently causes cancer.

Adult, differentiated cells can be reprogrammed to induced pluripotent stem cell; which can then be reprogrammed to heart muscle, skin, etc, to repair damaged tissue (to limited extent in clinical practice).

ChIPathlon: Evaluate the performance of all transcription factor mapping (peak calling) methods. To this end, we will develop a scalable and easy to use super computing pipeline to stage data, compare many different peak calling and differential binding site tools, and store all results into a single database.