Direct Involvement of Type II Secretion System in Extracellular Translocation of Shewanella oneidensis Outer Membrane Cytochromes MtrC and OmcA

Authors

• Liang Shi, Pacific Northwest National LaboratoryFollow
• Shuang Deng, Pacific Northwest National Laboratory
• Matthew Marshall, Pacific Northwest National Laboratory
• Zheming Wang, Pacific Northwest National LaboratoryFollow
• David Kennedy, Pacific Northwest National LaboratoryFollow
• Alice Dohnalkova, Pacific Northwest National LaboratoryFollow
• Heather Mottaz, Pacific Northwest National Laboratory
• Eric Hill, Pacific Northwest National Laboratory
• Yuri Gorby, J. Craig Venter Institute
• Alexander Beliaev, Pacific Northwest National LaboratoryFollow
• David Richardson, University of East AngliaFollow
• John M. Zachara, Pacific Northwest National LaboratoryFollow
• James K. Fredrickson, Pacific Northwest National LaboratoryFollow

Date of this Version

2008

Citation

JOURNAL OF BACTERIOLOGY, Aug. 2008, p. 5512–5516 Vol. 190, No. 15; doi:10.1128/JB.00514-08

Abstract

MtrC and OmcA are cell surface-exposed lipoproteins important for reducing solid metal oxides. Deletions of type II secretion system (T2SS) genes reduced their extracellular release and their accessibility to the proteinase K treatment, demonstrating the direct involvement of T2SS in translocation of MtrC and OmcA to the bacterial cell surface.