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Three hybrids with different kernel traits and feeding value were selected from a previous study to determine effects of corn hybrid and processing method (high-moisture corn (HMC), or dry-rolled corn DRC)) on nutrient digestibility and ruminal fermentation. DMI, intake rate, and total time spent eating were greater for HMC than DRC. Changes in ruminal pH and pH variance were also greater for HMC compared to DRC. Total-tract nutrient digestibility was influenced by processing method and hybrid. Nutrient digestibilities were greatest for hybrid 1, and greater for HMC compared to DRC. There was a hybrid by processing method interaction for molar proportions of propionate and the acetate: propionate (A:P) ratio. The magnitude of change for propionate molar proportions and the A:P ratio were different among hybrids when fed as HMC compared to DRC. Selection of hybrids with softer kernel traits and use of HMC will result in greater digestibility and favorable ruminal fermentation end products such as propionate.