School of Biological Sciences
University of Nebraska
Lincoln, NE 68588
E-mail: jstorz2@unl.edu
The primary focus of my research is the genetic basis of adaptive evolutionary change. One of the main goals is to understand the role of selection in shaping patterns of adaptive genetic variation in natural populations. On a more macroevolutionary timescale, we are investigating the differential gain and loss of genes from homologous gene families as a source of functional variation among the genomes of different species. Research in my lab integrates molecular population genetics, molecular evolution, comparative genomics, and experimental studies of protein function.
Lab homepage: http://biosci-labs.unl.edu/storz/index.html
Complete list of publications with links to pdfs: http://biosci-labs.unl.edu/storz/publications.html
2013
Epistasis Among Adaptive Mutations in Deer Mouse Hemoglobin, Chandrasekhar Natarajan, Noriko Inoguchi, Roy E. Weber, Angela Fago, Hideaki Moriyama, and Jay F. Storz
2012
Regulatory changes contribute to the adaptive enhancement of thermogenic capacity in high-altitude deer mice, Zachary A. Cheviron, Gwendolyn C. Bachman, Alex D. Connaty, and Jay F. Storz
Oxygenation properties and oxidation rates of mouse hemoglobins that differ in reactive cysteine content, Jay F. Storz, Roy E. Weber, and Angela Fago
2011
Differential Loss and Retention of Cytoglobin, Myoglobin, and Globin-E during the Radiation of Vertebrates, Federico G. Hoffmann, Juan C. Opazo, and Jay F. Storz
Expression and Purification of Recombinant Hemoglobin in Escherichia coli, Chandrasekhar Natarajan, Xiaoben Jiang, Angela Fago, Roy E. Weber, Hideaki Moriyama, and Jay F. Storz
Evolutionary Origins of Oxygen Sensing in Animals, Kalle T. Rytkönen and Jay F. Storz
Developmental regulation of hemoglobin synthesis in the green anole lizard Anolis carolinensis, Jay F. Storz, Federico G. Hoffmann, Juan C. Opazo, Thomas J. Sanger, and Hideaki Moriyama
Phylogenetic Diversification of the Globin Gene Superfamily in Chordates, Jay F. Storz, Juan C. Opazo, and Federico G. Hoffmann
Experimental Approaches to Evaluate the Contributions of Candidate Protein-Coding Mutations to Phenotypic Evolution, Jay F. Storz and Anthony J. Zera
2010
Molecular basis of a novel adaptation to hypoxic-hypercapnia in a strictly fossorial mole, Kevin L. Campbell, Jay F. Storz, Anthony V. Signore, Hideaki Moriyama, Kenneth C. Catania, Alexander P. Payson, Joseph Bonaventura, Jörg Stetefeld, and Roy E. Weber
Gene cooption and convergent evolution of oxygen transport hemoglobins in jawed and jawless vertebrates, Federico G. Hoffmann, Juan C. Opazo, and Jay F. Storz
Lineage-Specific Patterns of Functional Diversification in the α- and β-Globin Gene Families of Tetrapod Vertebrates, Federico G. Hoffmann, Jay F. Storz, Thomas A. Gorr, and Juan C. Opazo
Structure and Reactivity of Hexacoordinate Hemoglobins, Smita Kakar, Federico G. Hoffmann, Jay F. Storz, Marian Fabian, and Mark S. Hargrove
Genes for High Altitudes, Jay F. Storz
Genetic differences in hemoglobin function between highland and lowland deer mice, Jay F. Storz, Amy M. Runck, Hideaki Moriyama, Roy E. Weber, and Angela Fago
Phenotypic plasticity and genetic adaptation to high-altitude hypoxia in vertebrates, Jay F. Storz, Graham R. Scott, and Zachary A. Cheviron
Integrating Evolutionary and Functional Approaches to Infer Adaptation at Specific Loci, Jay F. Storz and Christopher W. Wheat
2009
Molecular evolution of cytochrome b in high- and low-altitude deer mice (genus Peromyscus), E. J. Gering, J. C. Opazo, and Jay F. Storz
Origin and Ascendancy of a Chimeric Fusion Gene: The β/δ-Globin Gene of Paenungulate Mammals, Juan C. Opazo, Angela M. Sloan, Kevin L. Campbell, and Jay F. Storz
Evolution of Duplicated β-Globin Genes and the Structural Basis of Hemoglobin Isoform Differentiation in Mus, Amy M. Runck, Hideaki Moriyama, and Jay F. Storz
Gene Duplication and the Resolution of Adaptive Conflict, Jay F. Storz
Evolutionary and functional insights into the mechanism underlying high-altitude adaptation of deer mouse hemoglobin, Jay F. Storz, Amy M. Runck, Stephen J. Sabatino, John K. Kelly, Nuno Ferrand, Hideaki Moriyama, Roy E. Weber, and Angela Fago
2008
Evidence for contrasting modes of selection at interacting globin genes in the European rabbit (Oryctolagus cuniculus), R. Campos, Jay F. Storz, and N. Ferrand
Molecular evolution of cytochrome b in high- and low-altitude deer mice (genus Peromyscus), E.J. Gering, J. C. Opazo, and Jay F. Storz
Rapid Rates of Lineage-Specific Gene Duplication and Deletion in the α-Globin Gene Family, Federico G. Hoffmann, Juan C. Opazo, and Jay F. Storz
New Genes Originated via Multiple Recombinational Pathways in the β-Globin Gene Family of Rodents, Frederico Hoffmann, Juan Opazo, and Jay F. Storz
Genomic evidence for independent origins of β-like globin genes in monotremes and therian mammals, Juan C. Opazo, Federico G. Hoffmann, and Jay F. Storz
Differential loss of embryonic globin genes during the radiation of placental mammals, Juan C. Opazo, Federico Hoffmann, and Jay F. Storz
Adaptive Functional Divergence among Triplicated α-Globin Genes in Rodents, Jay F. Storz, Federico G. Hoffmann, Juan C. Opazo, and Hideaki Moriyama
Effects of Spatially Varying Selection on Nucleotide Diversity and Linkage Disequilibrium: Insights From Deer Mouse Globin Genes, Jay F. Storz and John K. Kelly
2007
The αD-Globin Gene Originated via Duplication of an Embryonic α-Like Globin Gene in the Ancestor of Tetrapod Vertebrates, Federico G. Hoffmann and Jay F. Storz
HEMOGLOBIN FUNCTION AND PHYSIOLOGICAL ADAPTATION TO HYPOXIA IN HIGH-ALTITUDE MAMMALS, Jay F. Storz
Complex Signatures of Selection and Gene Conversion in the Duplicated Globin Genes of House Mice, Jay F. Storz, Monica Baze, Jessica L. Waite, Federico G. Hoffmann, Juan C. Opazo, and Jack P. Hayes
THE STUDY OF ADAPTATION AND SPECIATION IN THE GENOMIC ERA, Jay F. Storz and Hopi E. Hoekstra
Supporting Information for "The Molecular Basis of High-Altitude Adaptation in Deer Mice", Jay F. Storz, Stephen J. Sabatino, Federico G. Hoffmann, Eben J. Gering, Hideaki Moriyama, Nuno Ferrand, Bruno Monteiro, and Michael W. Nachman
The Molecular Basis of High-Altitude Adaptation in Deer Mice, Jay F. Storz, Stephen J. Sabatino, Federico G. Hoffmann, Eben J. Gering, Hideaki Moriyama, Nuno Ferrand, Bruno Monteiro, and Michael W. Nachman
2006
Evolutionary Dynamics of the Short-Nosed Fruit Bat, Cynopterus sphinx (Pteropodidae): Inferences from the Spatial Scale of Genetic and Phenotypic Differentiation, Jay F. Storz, Hari R. Bhat, Johnson Balasingh, P. Thiruchenthil Nathan, and Thomas H. Kunz
2005
Nonrandom dispersal and local adaptation, Jay F. Storz
Using genome scans of DNA polymorphism to infer adaptive population divergence, Jay F. Storz
2004
Estimation of genetically effective breeding numbers using a rejection algorithm approach, Uma Ramakrishnan, Jay F. Storz, Barbara L. Taylor, and Russell Lande
Natural Selection Drives Altitudinal Divergence at the Albumin Locus in Deer Mice, Peromyscus Maniculatus, Jay F. Storz and Jean M. Dubach
Genome Scans of DNA Variability in Humans Reveal Evidence for Selective Sweeps Outside of Africa, Jay F. Storz, Bret A. Payseur, and Michael W. Nachman
2003
Natural Selection on Protein Polymorphism in the Rodent Genus Peromyscus: Evidence from Interlocus Contrasts, Jay F. Storz and Michael W. Nachman
2002
Contrasting Patterns of Divergence in Quantitative Traits and Neutral DNA Markers: Analysis of Clinal Variation, Jay F. Storz
Testing for Genetic Evidence of Population Expansion and Contraction: An Empirical Analysis of Microsatellite DNA Variation Using a Hierarchical Bayesian Model, Jay F. Storz and Mark Beaumont
Genetic Evidence for Long-Term Population Decline in a Savannah Dwelling Primate: Inferences from a Hierarchical Bayesian Model, Jay F. Storz, Mark A. Beaumont, and Susan C. Alberts
Genetic Effective Size of a Wild Primate Population: Influence of Current and Historical Demography, Jay F. Storz, Uma Ramakrishnan, and Susan C. Alberts
2001
Clinal variation in body size and sexual dimorphism in an Indian fruit bat, Cynopterus sphinx (Chiroptera: Pteropodidae), Jay F. Storz, J. Balasingh, Hari Bhat, P. Thiruchenthil Nathan, D. Paramanantha Swami Doss, A. Antony Prakash, and Thomas H. Kunz
Genetic Consequences of Polygyny and Social Structure in an Indian Fruit Bat, Cynopterus sphinx. I. Inbreeding, Outbreeding, and Population Subdivision, Jay F. Storz, Hari Bhat, and Thomas Kunz
Genetic Consequences of Polygyny and Social Structure in an Indian Fruit Bat, Cynopterus sphinx. II. Variance in Male Mating Success and Effective Population Size, Jay F. Storz, Hari Bhat, and Thomas H. Kunz
Determinants of Effective Population Size for Loci with Different Modes of Inheritance, Jay F. Storz, U. Ramakrishnan, and S. C. Alberts
2000
Variation at tri- and tetranucleotide repeat microsatellite loci in the fruit bat genus Cynopterus (Chiroptera: Pteropodidae), Jay F. Storz
Dispersion and site fidelity in a tent-roosting population of the short-nosed fruit bat (Cynopterus sphinx) in southern India, Jay F. Storz, J. Balasingh, P. Thiruchenthil Nathan, K. Emmanuel, and Thomas H. Kunz
Social structure of a polygynous tent-making bat, Cynopterus sphinx (Megachiroptera), Jay F. Storz, Hari Bhat, and Thomas H. Kunz
1999
Genetic Consequences of Mammalian Social Structure, Jay F. Storz
Cynopterus sphinx, Jay F. Storz and Thomas H. Kunz
1997
Selective Feeding by Phyllostomid Fruit Bats in a Subtropical Montane Cloud Forest, David Herníndez-Conrique, Luis Iñiguez-Dávalos, and Jay F. Storz