Papers in the Biological Sciences

 

Date of this Version

5-2016

Citation

Physiology (Bethesda). 2016 May; 31(3): pp. 223–232.

Comments

Copyright © 2016 Int. Union Physiol. Sci./Am. Physiol. Soc. Used by permission.

Abstract

During vertebrate evolution, duplicated hemoglobin (Hb) genes diverged with respect to functional properties as well as the developmental timing of expression. For example, the subfamilies of genes that encode the different subunit chains of Hb are ontogenetically regulated such that functionally distinct Hb isoforms are expressed during different developmental stages. In some vertebrate taxa, functional differentiation between co-expressed Hb isoforms may also contribute to physiologically important divisions of labor.

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