The papers in this series relate to public health issues of interest or importance to residents of Nebraska and the Great Plains. The papers archived here are either published under Creative Commons license or are not subject to copyright restrictions by virtue of having been authored by United States government officials or employees (US EPA, USDA, NASA, NOAA, CDC, USGS, etc.).

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2021

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IFNγ is a key link between obesity and Th1-mediated autoimmune diseases, Heekyong R. Bae, Myung-Sook Choi, Suntae Kim, Howard A. Young, M E. Gershwin, Seon Min Jeon, and Eun Young Kwon

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Using PET imaging to track STING-induced interferon signaling, Enitome E. Bafor and Howard A. Young

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Discussion of “Is group testing ready for prime-time in disease Identification?” by Haber, Malinovsky, and Albert, Statistics in Medicine, 2021, Brad J. Biggerstaff

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Lessons learned: new insights on the role of cytokines in COVID-19, Maja Buszko, Aleksandra Nita-Lazar, Jung Hyun Park, Pamela L. Schwartzberg, Daniela Verthelyi, Howard A. Young, and Amy S. Rosenberg

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The Experts Speak: A New Feature in the JICR, Michael Gale, Ram Savan, Adolfo Garcia-Sastre, Ludmila Prokunina-Olsso, Kuppusamy Balamurugan, and Howard A. Young

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Cytokines: From Clinical Significance to Quantification, Chao Liu, Dewei Chu, Kourosh Kalantar-Zadeh, Jacob George, Howard A. Young, and Guozhen Liu

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Promise and complexity of lupus mouse models, Erica Moore, Joshua A. Reynolds, Anne Davidson, Stefania Gallucci, Laurence Morel, Deepak A. Rao, Howard A. Young, and Chaim Putterman

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Natural Killer Cell Transcript 4 promotes the development of Sjӧgren's syndrome via activation of Rap1 on B cells, Peng Qu, Todd Wuest, Yongfen Min, Ilias Alevizos, Howard A. Young, and P. Charles Lin

2020

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Multi-omics: Differential expression of IFN-γ results in distinctive mechanistic features linking chronic inflammation, gut dysbiosis, and autoimmune diseases, Heekyong R. Bae, Patrick S.C. Leung, Deborah L. Hodge, John M. Fenimore, Seon Min Jeon, Vishal Thovarai, Amiran Dzutsev, Andrew A. Welcher, Michael Boedigheimer, Michael A. Damore, Myung Sook Choi, Richard A. Fravell, Giorgio Trinchieri, M. Eric Gershwin, and Howard A. Young

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The dynamic changes in cytokine responses in COVID-19: a snapshot of the current state of knowledge, Maja Buszko, Jung Hyun Park, Daniela Verthelyi, Ranjan Sen, Howard A. Young, and Amy S. Rosenberg

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Adaptive in vivo device for theranostics of inflammation: Real-time monitoring of interferon-γ and aspirin, Chaomin Cao, Ronghua Jin, Hui Wei, Zhongning Liu, Shengnan Ni, Guo Jun Liu, Howard A. Young, Xin Chen, and Guozhen Liu

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On the Inadequacy of Species Distribution Models for Modelling the Spread of SARS-CoV-2: Response to Araújo and Naimi, Joseph D. Chipperfield, Blas M. Benito, Robert B. O'Hara, Richard J. Telford, and Colin J. Carlson

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Multistate Mumps Outbreak Originating from Asymptomatic Transmission at a Nebraska Wedding — Six States, August–October 2019, Matthew Donahue, Blake Hendrickson, Derek Julian, Nicholas Hill, Julie Rother, Samir Koirala, Joshua L. Clayton, Thomas Safranek, and Bryan Buss

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Perforin-deficient CAR T cells recapitulate late-onset inflammatory toxicities observed in patients, Kazusa Ishii, Marie Pouzolles, Christopher D. Chien, Rebecca A. Erwin-Cohen, M. Eric Kohler, Haiying Qin, Haiyan Lei, Skyler Kuhn, Amanda K. Ombrello, Alina Dulau-Florea, Michael A. Eckhaus, Haneen Shalabi, Bonnie Yates, Daniel A. Lichtenstein, Valérie S. Zimmermann, Taisuke Kondo, Jack F. Shern, Howard A. Young, Naomi Taylor, Nirali N. Shah, and Terry J. Fry

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Evaluating Gene Drive Approaches for Public Benefit, Michael R. Santos

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The Gut Microbiome and Xenobiotics: Identifying Knowledge Gaps, Vicki L. Sutherland, Charlene A. Mcqueen, Donna Mendrick, Donna Gulezian, Carl Cerniglia, Steven Foley, Sam Forry, Sangeeta Khare, Xue Liang, Jose E. Manautou, Donald Tweedie, Howard A. Young, Alexander V. Alekseyenko, Frank Burns, Rod Dietert, Alan Wilson, and Connie Chen

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Dynamics of genomic and immune responses during primary immunotherapy resistance in mismatch repair–deficient tumors, Nobuyuki Takahashi, Vinodh N. Rajapakse, Lorinc Pongor, Suresh Kumar, Camille Tlemsani, Rebecca Erwin-Cohen, Howard A. Young, Stephen Hewitt, Jun S. Wei, Javed Khan, Alejandro V. Villarino, Jane B. Trepel, and Anish Thomas

2019

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Thymic expression of IL-4 and IL-15 after systemic inflammatory or infectious Th1 disease processes induce the acquisition of"innate" characteristics during CD8 + T cell development, Natalia S. Baez, Fabio Cerbán, Constanza Savid-Frontera, Deborah L. Hodge, Jimena Tosello, Eva Acosta-Rodriguez, Laura Almada, Adriana Gruppi, Maria Estefania Viano, Howard A. Young, and Maria Cecilia Rodriguez-Galan

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IFN-Γ: A cytokine at the right time, is in the right place, J. Daniel Burke and Howard A. Young

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Report on the 2018 cancer, autoimmunity, and immunology conference, Colleen S. Curran, Connie L. Sommers, Howard A. Young, Katarzyna Bourcier, Marie Mancini, and Elad Sharon

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A phase I/II study of pemetrexed with sirolimus in advanced, previously treated non-small cell lung cancer, Takefumi Komiya, Regan M. Memmott, Gideon M. Blumenthal, Wendy Bernstein, Marc S. Ballas, Roopa De Chowdhurry, Guinevere Chun, Cody J. Peer, William D. Figg, David J. Liewehr, Seth M. Steinberg, Giuseppe Giaccone, Eva Szabo, Shigeru Kawabata, Junji Tsurutani, Arun Rajan, and Phillip A. Dennis

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Partners in Crime: Fledgling Tumors Hijack Inflammation, Balamurugan Kuppusamy and Howard A. Young

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Meeting Overview: Interferon Lambda - Disease Impact and Therapeutic Potential, Thomas R. O'Brien, Howard A. Young, Raymond P. Donnelly, and Ludmila Prokunina-Olsson

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Critical role of post-transcriptional regulation for IFN-γ in tumor-infiltrating T cells, Fiamma Salerno, Aurelie Guislain, Julian J. Freen-Van Heeren, Benoit P. Nicolet, Howard A. Young, and Monika C. Wolkers

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Post–Modern Epidemiology: When Methods Meet Matter, George Davey Smith

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Density of σ70 promoter-like sites in the intergenic regions dictates the redistribution of RNA polymerase during osmotic stress in Escherichia coli, Zhe Sun, Cedric Cagliero, Jerome Izard, Yixiong Chen, Yan Ning Zhou, William F. Heinz, Thomas D. Schneider, and Ding Jun Jin

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Durvalumab in Combination with Olaparib in Patients with Relapsed SCLC: Results from a Phase II Study, Anish Thomas, Rasa Vilimas, Christopher Trindade, Rebecca Erwin-Cohen, Nitin Roper, Liqiang Xi, Venkatesh Krishnasamy, Elliot Levy, Andy Mammen, Samantha Nichols, Yuanbin Chen, Vamsidhar Velcheti, Faye Yin, Eva Szabo, Yves Pommier, Seth M. Steinberg, Jane B. Trepel, Mark Raffeld, Howard A. Young, Javed Khan, Stephen Hewitt, and Jung Min Lee

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Ion Gresser 1928-2019, Jan Vilcek and Howard A. Young

2018

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Student Mental Health and Resources

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The interplay of type I and type II interferons in murine autoimmune cholangitis as a basis for sex-biased autoimmunity, Heekyong R. Bae, Deborah L. Hodge, Guo Xiang Yang, Patrick S.C. Leung, Sathi Babu Chodisetti, Julio C. Valencia, Michael Sanford, John M. Fenimore, Ziaur S.M. Rahman, Koichi Tsuneyama, Gary L. Norman, M E. Gershwin, and Howard A. Young

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Mammalian Pathogenesis and Transmission of Avian Influenza A(H7N9) Viruses, Tennessee, USA, 2017, Jessica A. Belser, Nicole Brock, Xiangjie Sun, Joyce Jones, Natosha Zanders, Erin Hodges, Joanna A. Pulit-Penaloza, David Wentworth, Terrence M. Tumpey, Todd Davis, and Taronna R. Maines

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Methylation-based enrichment facilitates low-cost, noninvasive genomic scale sequencing of populations from feces, Kenneth L. Chiou and Christina M. Bergey

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Interferon-gamma impairs maintenance and alters hematopoietic support of bone marrow mesenchymal stromal cells, Marieke Goedhart, Anne S. Cornelissen, Carlijn Kuijk, Sulima Geerman, Marion Kleijer, Jaap D. Van Buul, Stephan Huveneers, Marc H.G.P. Raaijmakers, Howard A. Young, Monika C. Wolkers, Carlijn Voermans, and Martijn A. Nolte

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Early TCR Signaling Induces Rapid Aerobic Glycolysis Enabling Distinct Acute T Cell Effector Functions, Ashley V. Menk, Nicole E. Scharping, Rebecca S. Moreci, Xue Zeng, Cliff Guy, Sonia Salvatore, Heekyong Bae, Jianxin Xie, Howard A. Young, Stacy Gelhaus Wendell, and Greg M. Delgoffe

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Translational repression of pre-formed cytokine-encoding mRNA prevents chronic activation of memory T cells, Fiamma Salerno, Sander Engels, Maartje van den Biggelaar, Floris P.J. van Alphen, Aurelie Guislain, Wanqi Zhao, Deborah L. Hodge, Sarah E. Bell, Jan Paul Medema, Marieke von Lindern, Martin Turner, Howard A. Young, and Monika C. Wolkers

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Therapeutic and immunological interventions in primary biliary cholangitis: From mouse models to humans, Atsushi Tanaka, Patrick S.C. Leung, Howard A. Young, and M. Eric Gershwin

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TipSheet: Student Mental Health and Resources, UNL Office of the Executive Vice Chancellor

2017

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Acute maternal oxidant exposure causes susceptibility of the fetal brain to inflammation and oxidative stress, Feroz Akhtar, Christopher A. Rouse, Gabriel Catano, Marcus Montalvo, Sarah L. Ullevig, Reto Asmis, Kusum K. Kharbanda, and Shivani K. Maffi

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Improving community readiness for change through coalition capacity building: Evidence from a multisite intervention, Kaston D. Anderson-Carpenter, Jomella Watson-Thompson, Marvia D. Jones, and Lisa Chaney

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Improving community readiness for change through coalition capacity building: Evidence from amultisite intervention, Kaston D. Anderson-Carpenter, Jomella Watson-Thompson, Marvia D. Jones, and Lisa Chaney

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Role of H7 hemagglutinin in murine infectivity of influenza viruses following ocular inoculation, Jessica A. Belser, Xiangjie Sun, Hannah M. Creager, Adam Johnson, Callie Ridenour, Li-Mei Chen, Terrence M. Tumpey, and Taronna R. Maines

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Neoadjuvant treatment of pancreatic adenocarcinoma: a systematic review and meta-analysis of 5520 patients, Mashaal Dhir, Gautam K. Malhotra, Davendra P. S. Sohal, Nicholas A. Hein, Lynette M. Smith, Eileen M. O'Reilly, Nathan Bahary, and Chandrakanth Are

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Current prospects of type II interferon γ signaling & autoimmunity, Daniel S. Green, Howard A. Young, and Julio C. Valencia

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Kinase Suppressor of Ras 2 (KSR2) expression in the brain regulates energy balance and glucose homeostasis, Lili Guo, Diane L. Costanzo-Garvey, Deandra R. Smith, Beth K. Neilsen, Richard G. MacDonald, and Robert E. Lewis

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A prospective study of cancer risk among Agricultural Health Study farm spouses associated with personal use of organochlorine insecticides, Lydia M. Louis, Catherine C. Lerro, Melissa C. Friesen, Gabriella Andreotti, Stella Koutros, Dale P. Sandler, Aaron Blair, Mark G. Robson, and Laura E. Beane Freeman

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National and State-Specific Shingles Vaccination Among Adults Aged >60 Years, Peng-jun Lu, Alissa O'Halloran, Walter W. Williams, and Rafael Harpaz

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Smoking and finances: baseline characteristics of low income daily smokers in the FISCALS cohort, Kristy A. Martire, Philip Clare, Ryan J. Courtney, Billie Bonevski, Veronica Boland, Ron Borland, Christopher M. Doran, Michael Farrell, Wayne Hall, Jaimi M. Iredale, Mohammad Siahpush, and Richard P. Mattick

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Adverse childhood experiences and life opportunities: Shifting the narrative, Marilyn Metzler, Melissa T. Merrick, Joanne Flevens, and Katie A. Ports

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Using Cerebrospinal Fluid Biomarker Testing to Target Treatment to Patients with Mild Cognitive Impairment: A Cost-Effectiveness Analysis, Tzeyu L. Michaud, Robert L. Kane, J. Riley McCarten, Joseph E. Gaugler, John A. Nyman, and Karen M. Kuntz

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Evaluation of divided attention psychophysical task performance and effects on pupil sizes following smoked, vaporized and oral cannabis administration, Matthew N. Newmeyer, Madeleine J. Swortwood, Megan E. Taylor, Osama A. Abulseoud, Thomas H. Woodward, and Marilyn A. Huestis

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Repealing the ACA without a Replacement — The Risks to American Health Care, Barack Obama

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Nanoscale Characterization of Interaction of APOBEC3G with RNA, Yangang Pan, Zhiqiang Sun, Atanu Maiti, Tapan Kanai, Hiroshi Matsuo, Ming Li, Reuben S. Harris, Luda S. Shlyakhtenko, and Yuri L. Lyubchenko

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Cost-Benefit Analysis of Two Child Abuse and Neglect Primary Prevention Programs for US States, Cora Peterson, Curtis Florence, Robert Thomas, and Joanne Klevens

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Th1 Differentiation Drives the Accumulation of Intravascular, Non-protective CD4 T Cells during Tuberculosis, Michelle A. Sallin, Shunsuke Sakai, Keith D. Kauffman, Howard A. Young, Jinfang Zhu, and Daniel L. Barber

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Rapid and rigorous IL-17A production by a distinct subpopulation of effector memory T lymphocytes constitutes a novel mechanism of toxic shock syndrome immunopathology, Peter A. Szabo, Ankur Goswami, Delfina M. Mazzuca, Kyoungok Kim, David B. O'Gorman, David A. Hess, Ian D. Welch, Howard A. Young, Bhagirath Singh, John K. McCormick, and S. M.Mansour Haeryfar

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Toward solving the etiological mystery of primary biliary cholangitis, Atsushi Tanaka, Patrick S.C. Leung, Howard A. Young, and M. Eric Gershwin

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Looming Threats and Animacy: Reduced Responsiveness in Youth with Disrupted Behavior Disorders, Stuart F. White, Laura C. Thornton, Joseph Leshin, Roberta Clanton, Stephen Sinclair, Dionne Coker-Appiah, Harma Meffert, Soonjo Hwang, and James R. Blair

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Trends of lack of health insurance among US adults aged 18-64 years: findings from the Behavioral Risk Factor Surveillance System, 1993-2014, G. Zhao, C. A. Okoro, S. S. Dhingra, F. Xu, and M. Zack

2016

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Use of claims data to estimate annual cervical cancer screening percentages in Portland metropolitan area, Oregon, Nasreen Abdullah, Robert S. Laing, Susan Hariri, Collette M. Young, and Sean Schafer

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Design and methods of a social network isolation study for reducing respiratory infection transmission: The eX-FLUcluster randomized trial, Allison E. Aiello, Amanda M. Simanek, Marisa C. Eisenberg, Alison R. Walsh, Brian Davis, Eric Volz, Caroline Cheng, Jeanette J. Rainey, Amra Uzicanin, Hongjiang Gao, Nathaniel Osgood, Dylan Knowles, Kevin Stanley, Kara Tarter, and Arnold S. Monto

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The association of urinary polycyclic aromatic hydrocarbon biomarkers and cardiovascular disease in the US population, Omayma Alshaarawy, Hosam A. Elbaz, and Michael E. Andrew

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The epidemiology and outcomes of invasive Candida infections among organ transplant recipients in the United States: results of the Transplant-Associated Infection Surveillance Network (TRANSNET), David R. Andes, Nasia Safdar, John W. Baddley, Barbara Alexander, Lisa Brumble, Allison Freifeld, Susan Hadley, Loreen Herwaldt, Carol Kauffman, G. Marshall Lyon, Vicki Morrison, Thomas Patterson, Trish Perl, Randall Walker, Tim Hess, Tom Chiller, Peter G. Pappas, and The TRANSNET Investigators

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The epidemiology and outcomes of invasive Candida infections among organ transplant recipients in the United States: results of the Transplant-Associated Infection Surveillance Network (TRANSNET), David R. Andes, Nasia Safdar, John W. Baddley, Barbara Alexander, Lisa Brumble, Allison Freifeld, Susan Hadley, University of Iowa School of Medicine, Carol Kauffman, G. Marshall Lyon, Vicki Morrison, Thomas Patterson, Trish Perl, Randall Walker, Tim Hess, Centers for Disease Control and Prevention, and Peter G. Pappas

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Chronic expression of interferon-gamma leads to murine autoimmune cholangitis with a female predominance, Heekyong R. Bae, Patrick S.C. Leung, Koichi Tsuneyama, Julio C. Valencia, Deborah L. Hodge, Seohyun Kim, Tim Back, Megan Karwan, Anand S. Merchant, Nobuyuki Baba, Dechun Feng, Ogyi Park, Bin Gao, Guo Xiang Yang, M. Eric Gershwin, and Howard A. Young

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Epidemiology of human leptospirosis in Malaysia, 2004–2012, Douadi Benacer, Kwai Lin Thong, Ng Choung Min, Khebir Bin Verasahib, Renee L. Galloway, Rudy A. Hartskeerl, Marc Souris, and Siti Nursheena Mohd Zain

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Possible Airborne Person-to-Person Transmission of Mycobacterium bovis — Nebraska 2014–2015, Bryan F. Buss, Alison Keyser-Metobo, Julie Rother, Laura Holtz, Kristin Gall, John Jereb, Caitlin N. Murphy, Peter C. Iwen, Suelee Robbe-Austerman, Melissa A. Holcomb, and Pat Infield

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Population-Based Microcephaly Surveillance in the United States, 2009 to 2013: An Analysis of Potential Sources of Variation, Janet D. Cragan, Jennifer L. Isenburg, Samantha E. Parker, C. J. Alverson, Robert E. Meyer, Erin B. Stallings, Russell S. Kirby, Philip J. Lupo, Jennifer S. Liu, Amanda Seagroves, Mary K. Ethen, Sook Ja Cho, MaryAnn Evans, Rebecca F. Liberman, Jane Fornoff, Marilyn L. Browne, Rachel E. Rutkowski, Amy E. Nance, Marlene Anderka, Deborah J. Fox, Amy Steele, Glenn Copeland, Paul A. Romitti, and Cara T. Mai

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Population-Based Microcephaly Surveillance in the United States, 2009 to 2013: An Analysis of Potential Sources of Variation, Janet D. Cragan, Jennifer L. Isenburg, Samantha E. Parker, C. J. Alverson, Robert E. Meyer, Erin B. Stallings, Russell S. Kirby, Philip J. Lupo, Jennifer S. Liu, Amanda Seagroves, Mary K. Ethen, Sook Ja Cho, MaryAnn Evans, Rebecca F. Liberman, Jane Fornoff, Marilyn L. Browne, Rachel E. Rutkowski, Amy E. Nance, Marlene Anderka, Deborah J. Fox, Amy Steele, Glenn Copeland, Paul A. Romitti, and Cara T. Mai

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Geographic Accessibility of Pulmonologists for Adults With COPD, Janet B. Croft, Hua Lu, Xingyou Zhang, and James B. Holt

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Regulation of IFN-γ expression, John Fenimore and Howard A. Young

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Age-Related Disparities in Trauma Center Access for Severe Head Injuries Following the Release of the Updated Field Triage Guidelines, Thomas J. Flottemesch; Susan Raetzman; Kevin C. Heslin; Katie Fingar; Rosanna Coffey; M.L. Barrett, Inc.; and Ernest Moy

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Magnitude and characteristics of acute paraquat- and diquat-related illnesses in the US: 1998–2013, Gamola Z. Fortenberry, John Beckman, Abby Schwartz, Joanne Bonnar Prado, Lucia S. Graham, Sheila Higgins, Michelle Lackovic, Prakash Mulay, Heidi Bojes, Justin Waltz, Yvette Mitchell, Kathy Leinenkugel, Michel S. Oriel, Elizabeth Evans, and Geoffrey M. Calvert

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Cell non-autonomous regulation of hepatic IGF-1 and neonatal growth by Kinase Suppressor of Ras 2 (KSR2), Lili Guo, Diane L. Costanzo-Garvey, Deandra R. Smith, Megan E. Zavorka, Megan Venable-Kang, Richard G. MacDonald, and Robert E. Lewis

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Parental Presence at the Bedside of a Child with Suspected Ebola: An Expert Discussion, Cynthia F. Hinton, H. Dele Davies, Susan N. Hocevar, Steven E. Krug, Aaron M. Milstone, Leonard Ortmann, Cynthia H. Cassell, Georgina Peacock, and STephanie E. Griese

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The Burden of Hepatitis C Infection–Related Liver Fibrosis in the United States, R. Monina Klevens, Lauren Canary, Xiaohua Huang, Maxine M. Denniston, Anthony E. Yeo, Rick L. Pesano, John W. Ward, and Scott Holmberg

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WHO consultation on group B Streptococcus vaccine development: Report from a meeting held on 27–28 April 2016, Miwako Kobayashi, Stephanie J. Schrag, Mark R. Alderson, Shabir A. Madhi, Carol J. Baker, Ajoke Sobanjo-ter Meulen, David C. Kaslow, Peter G. Smith, Vasee S. Moorthy, and Johan Vekemans

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Aging converts innate B1a cells into potent CD8+ T cell inducers, Catalina Lee-Chang, Monica Bodogai, Kanako Moritoh, Xin Chen, Robert Wersto, Ranjan Sen, Howard A. Young, Michael Croft, Luigi Ferrucci, and Arya Biragyn

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Meeting report: 4th ISIRV antiviral group conference: Novel antiviral therapies for influenza and other respiratory viruses, Jennifer L. McKimm-Breschkin and Alicia M. Fry

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Differences in Selected HIV Care Continuum Outcomes Among People Residing in Rural, Urban, and Metropolitan Areas—28 US Jurisdictions, John A. Nelson, Anna Kinder, Anna Satcher Johnson, H. Irene Hall, Xiaohong Hu, Donna Sweet, Alyssa Guido, Harold Katner, Jennifer Janelle, Maribel Gonzalez, Natalia Martinez Paz, Charlotte Ledonne, Jason Henry, Theresa Bramel, and Jeanne Harris

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Differences in Selected HIV Care Continuum Outcomes Among People Residing in Rural, Urban, and Metropolitan Areas—28 US Jurisdictions, John A. Nelson, Anna Kinder, Anna Satcher Johnson, H. Irene Hall, Xiaohong Hu, Donna Sweet, Alyssa Guido, Harold Katner, Jennifer Janelle, Maribel Gonzalez, Natalia Martinez Paz, Charlotte Ledonne, Jason Henry, Theresa Bramel, and Jeanne Harris

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Tobacco Use, Secondhand Smoke, and Smoke-Free Home Rules in Multiunit Housing, Kimberly H. Nguyen, Yessica Gomez, David M. Homa, and Brian A. King

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United States Health Care Reform Progress to Date and Next Steps, Barack H. Obama

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Standardizing the influenza neuraminidase inhibition assay among United States public health laboratories conducting virological surveillance, M. Okomo-Adhiambo, V.P. Mishin, K. Sleeman, E. Saguar, H. Guevara, E. Reisdorf, R.H. Griesser, K.J. Spackman, M. Mendenhall, M.P. Carlos, B. Healey, K. St. George, J. Laplante, T. Aden, S. Chester, X. Xu, and L.V. Gubareva

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US and territory telemedicine policies: identifying gaps in perinatal care, Ekwutosi M. Okoroh, Charlan D. Kroelinger, Alexander M. Smith, David A. Goodman, and Wanda D. Barfield

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Motorcycle helmet effectiveness in reducing head, face and brain injuries by state and helmet law, Cody S. Olsen, Andrea M. Thomas, Michael Singleton, Anna M. Gaichas, Tracy J. Smith, Gary A. Smith, Justin Peng, Michael J. Bauer, Ming Qu, Denise Yeager, Timothy Kerns, Cynthia Burch, and Lawrence J. Cook

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Monoclonal antibodies to human butyrylcholinesterase reactive with butyrylcholinesterase in animal plasma, Hong Peng

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Varicella Vaccine Effectiveness in Preventing Community Transmission in the 2-Dose Era, Dana Perella, Chengbin Wang, Rachel Civen, Kendra Viner, Karen Kuguru, Irini Daskalaki, D. Scott Schmid, Adriana S. Lopez, Hung Fu Tseng, E. Claire Newbern, Laurene Mascola, and Stephanie R. Bialek

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Vision 20/20: Molecular-guided surgical oncology based upon tumor metabolism or immunologic phenotype: Technological pathways for point of care imaging and intervention, Brian W. Poguea, Keith D. Paulsen, Kimberley S. Samkoe, Jonathan T. Elliott, Tayyaba Hasan, Theresa V. Strong, Daniel R. Draney, and Joachim Feldwisch

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Size and characteristics of the biomedical research workforce associated with U.S. National Institutes of Health extramural grants, Lindsay R. Pool, Robin M. Wagner, Lindsey L. Scott, Deepshikha RoyChowdhury, Rediet Berhane, Charles Wu, Katrina Pearson, Jennifer A. Sutton, and Walter T. Schaffer

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Assessing climate change and health vulnerability at the local level: Travis County, Texas, Natasha Prudent, Adele Houghton, and George Luber

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Hormonal contraception among electronic cigarette users and cardiovascular risk: a systematic review, Halley E.M. Riley, Erin Berry-Bibee, Lucinda J. England, Denise J. Jamieson, Polly A. Marchbanks, and Kathryn M. Curtis

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Annual Report to the Nation on the Status of Cancer, 1975-2012, Featuring the Increasing Incidence of Liver Cancer, A. Blythe Ryerson, Christie R. Eheman, Sean F. Altekruse, John W. Ward, Ahmedin Jemal, Recinda L. Sherman, S. Jane Henley, Deborah Holtzman, Andrew Lake, Anne-Michelle Noone, Robert N. Anderson, Jiemin Ma, Kathleen N. Ly, Kathleen A. Cronin, Lynne Penberthy, and Betsy A. Kohler

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CD4 T Cell-Derived IFN-γ Plays a Minimal Role in Control of Pulmonary Mycobacterium tuberculosis Infection and Must Be Actively Repressed by PD-1 to Prevent Lethal Disease, Shunsuke Sakai, Keith D. Kauffman, Michelle A. Sallin, Arlene H. Sharpe, Howard A. Young, Vitaly V. Ganusov, and Daniel L. Barber

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Complete Influenza Vaccination Trends for Children Six to Twenty-Three Months, Tammy A. Santibanez, Lisa A. Grohskopf, Yusheng Zhai, and Katherine E. Kahn

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Reductions in disease activity in the AMPLE trial: clinical response by baseline disease duration, Michael Schiff, Michael E Weinblatt, Robert M. Valente, Gustavo Citera, Michael Maldonado, Elena Massarotti, Yusuf Yazici, and Roy Fleischmann

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Measuring infrastructure: A key step in program evaluation and planning, Carol L. Schmitt, LaShawn Glasgow, S. Rene Lavinghouze, Patricia P. Pieker, Erika Fulmer, Kelly McAleer, and Todd Rogers

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Teens and seat belt use: What makes them click?, Ruth A. Shults, Tamara M. Haegerich, Geeta Bhat, and Xinjian Zhang

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Congenital syphilis: trends in mortality and morbidity in the United States, 1999 through 2013, John R. Su, Lesley C. Brooks, Darlene W. Davis, Elizabeth A. Torrone, Hillard S. Weinstock, and Mary L. Kamb

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Importance of implementation economics for program planning— evaluation of CDC’s colorectal cancer control program, Florence K.L. Tangka and Sujha Subramanian

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Multiple-locus variable-number tandem repeat analysis for strain discrimination of non-O157 Shiga toxin-producing Escherichia coli, Chris Timmons, Eija Trees, Efrain M. Ribot, Peter Gerner-Smidt, Patti LaFon, Sung Im, and Li Maria Ma