Biochemistry, Department of
Date of this Version
2018
Document Type
Article
Abstract
Model file name: 1lmb-TFdimer-mags-joints-jnd-sc1-8-parts-v4b.stl
Additional files: 1lmb-Lys-Ser-extras-v4b.stl and 1lmb-TFdimer-Leu-v4b.stl
Authors: Michelle E Howell, Karin van Dijk, Rebecca L Roston
This is a teaching model of a ribbon and stick representation of the transcription factor lambda repressor (PDB: 1lmb). Key amino acid residues are in stick representation to illustrate the interactions between the repressor and the DNA to which it binds. Some of these residues have been designed with sites to add magnets to illustrate these interactions. Sphere magnets with a 1/8” diameter can be purchased separately from K&J Magnets. Some of the residues can be interchanged with other amino acid residues to mimic and demonstrate the effect of mutations on the interaction with DNA. This model consists of 2 monomer subunits that can be connected to form a dimer, which can interact with a 19-bp DNA segment model and is designed to accompany a teaching module illustrating transcription factor-DNA binding. The printable model is already uploaded to Shapeways.com in the MacroMolecules shop under the name “Lambda repressor TF dimer”. This model has been printed successfully using these parameters on Shapeways’ laser sintering printer in the Strong & Flexible Plastic material.
1lmb-Lys-Ser-extras-v4b.stl (151 kB)
1lmb-TFdimer-Leu-v4b.blend (538 kB)
1lmb-TFdimer-Leu-v4b.stl (140 kB)
1lmb-TFdimer-v4b.blend (9848 kB)
1lmb-TFdimer-v4b.PNG (172 kB)
1lmb-TFdimer-v4b.stl (4139 kB)
Comments
Copyright 2018 Michelle E Howell, Karin van Dijk, Rebecca L Roston