Genome Sequence of the Attenuated Carbosap Vaccine Strain of Bacillus anthracis

Authors

Robin Harrington, National Biodefense Analysis and Countermeasures Center
Brian D. Ondov, National Biodefense Analysis and Countermeasures Center
Diana Radune, National Biodefense Analysis and Countermeasures Center
Mary Beth Friss, National Biodefense Analysis and Countermeasures Center
Joy Klubnik, National Biodefense Analysis and Countermeasures Center
Lynn Diviak, National Biodefense Analysis and Countermeasures Center
Jonathan Hnath, National Biodefense Analysis and Countermeasures Center
Stephen R. Cendrowski, National Biodefense Analysis and Countermeasures Center
Thomas E. Blank, National Biodefense Analysis and Countermeasures Center
David Karaolis, National Biodefense Analysis and Countermeasures Center
Arthur M. Friedlander, United States Army Medical Research Institute for Infectious Diseases
James P. Burans, National Biodefense Analysis and Countermeasures Center
M. J. Rosovitz, National Biodefense Analysis and Countermeasures Center
Todd Treangen, National Biodefense Analysis and Countermeasures Center
Adam M. Phillippy, National Biodefense Analysis and Countermeasures Center
Nicholas H. Bergman, National Biodefense Analysis and Countermeasures CenterFollow

Date of this Version

2013

Citation

Published in Genome Announc. (2013) 1(1):e00067-12. DOI:10.1128/ genomeA.00067-12.

Abstract

The Bacillus anthracis Carbosap genome, which includes the pXO1 and pXO2 plasmids, has been shown to encode the major B. anthracis virulence factors, yet this strain’s attenuation has not yet been explained. Here we report the draft genome sequence of this strain, and a comparison to fully virulent B. anthracis.