Genome Sequence of the Attenuated Carbosap Vaccine Strain of Bacillus anthracis

Authors

• Robin Harrington, National Biodefense Analysis and Countermeasures Center
• Brian D. Ondov, National Biodefense Analysis and Countermeasures Center
• Diana Radune, National Biodefense Analysis and Countermeasures Center
• Mary Beth Friss, National Biodefense Analysis and Countermeasures Center
• Joy Klubnik, National Biodefense Analysis and Countermeasures Center
• Lynn Diviak, National Biodefense Analysis and Countermeasures Center
• Jonathan Hnath, National Biodefense Analysis and Countermeasures Center
• Stephen R. Cendrowski, National Biodefense Analysis and Countermeasures Center
• Thomas E. Blank, National Biodefense Analysis and Countermeasures Center
• David Karaolis, National Biodefense Analysis and Countermeasures Center
• Arthur M. Friedlander, United States Army Medical Research Institute for Infectious Diseases
• James P. Burans, National Biodefense Analysis and Countermeasures Center
• M. J. Rosovitz, National Biodefense Analysis and Countermeasures Center
• Todd Treangen, National Biodefense Analysis and Countermeasures Center
• Adam M. Phillippy, National Biodefense Analysis and Countermeasures Center
• Nicholas H. Bergman, National Biodefense Analysis and Countermeasures CenterFollow

Document Type

Article

Date of this Version

2013

Citation

Published in Genome Announc. (2013) 1(1):e00067-12. DOI:10.1128/ genomeA.00067-12.

Abstract

The Bacillus anthracis Carbosap genome, which includes the pXO1 and pXO2 plasmids, has been shown to encode the major B. anthracis virulence factors, yet this strain’s attenuation has not yet been explained. Here we report the draft genome sequence of this strain, and a comparison to fully virulent B. anthracis.