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To be successful both domestically and internationally, biotechnology must establish an acceptable position in the sociopolitical framework. This United States (US) study assessed levels of awareness and acceptance of biotechnology issues among youth (n = 283), undergraduate students (n = 330), and adults (n = 166). The percentage of adults who were aware of how biotechnology would affect food, health, and the environment was almost three times that of youth respondents. It was concluded that consumer groups would most likely be impacted by accurate, unbiased agricultural biotechnology information delivered through the Internet and newspapers that originates from reliable, accessible, and science-based sources.