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A 2 × 3 factorial metabolism study using 6 ruminally and duodenally cannulated heifers evaluated the site and amount of nutrient digestion when feeding high protein dry distillers grains plus solubles (DDGS) or conventionally produced DDGS at 30% inclusion compared to feeding no distillers in either dry- rolled or steam- flaked corn diets. Apparent total tract starch digestibility was unaffected by distillers treatment in SFCbased diets, but decreased from 95.1% to 92.0% when DDGS was added to DRC diets, and further decreased to 88.7% for HiPro diets. Dry matter and OM digestibilities were lower types of when either DDGS diets were fed, but no differences were observed between conventional or high protein DDGS. Feeding high protein DDGS did not change digestion compared to conventional DDGS, despite higher CP content. Digestion is greater when cattle are fed steam- flaked corn compared to dry- rolled corn.