Department of Animal Science


Date of this Version

January 1999


Published in 1999 Nebraska Beef Cattle Report. Published by Agricultural Research Division & University of Nebraska Cooperative Extension , Institute of Agriculture and Natural Resources, University of Nebraska-Lincoln.


The ability of adenosine, insulin and human acylation-stimulating protein to modify fat synthesis was determined using cultures of fat tissue from steers. Adenosine did not influence fat synthesis. However, acylation stimulating protein and insulin promoted fat synthesis. These observations, coupled with knowledge of how fat synthesis is regulated in other species, justify investigation of whether cattle synthesize acylation-stimulating protein, and how this synthesis is regulated. An understanding of how acylation-stimulating protein production and action is regulated should expose potential places for intervention to manipulate fat synthesis in cattle.