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An experiment with 236 steers and eight pens per treatment (14 or 15 steers/pen) evaluated two grain adaptation treatments. Treatments included adapting steers by decreasing alfalfa (CON) or decreasing a combination of distillers grains and corn gluten feed (SYNERGY) followed by feeding a common finishing diet to slaughter. Performance and carcass traits did not differ between adaptation systems. A combination of MDGS and SYNERGY can be used to adapt beef cattle to feedlot diets with efficacy of the traditional, foragebased method.