Biochemistry, Department of
Accessibility Remediation
If you are unable to use this item in its current form due to accessibility barriers, you may request remediation through our remediation request form.
Document Type
Article
Date of this Version
2003
Citation
Microbiology And Molecular Biology Reviews, Sept. 2003, p. 454–472 Vol. 67, No. 3
Abstract
INTRODUCTION......................................................................................................................................................454
FATTY ACIDS AND BIOLOGICAL MEMBRANES.............................................................................................455
Fatty Acid Transport Defined ...............................................................................................................................456
MODEL SYSTEMS TO INVESTIGATE FATTY ACID TRANSPORT ..............................................................456
Genetic Foundations of Fatty Acid Transport....................................................................................................456
PROTEINS IMPLICATED IN FATTY ACID TRANSPORT ...............................................................................456
Fatty Acid Translocase..........................................................................................................................................457
Fatty Acid Binding Protein—Membrane Bound ................................................................................................457
Fatty Acid Transport Protein...............................................................................................................................458
The Long-Chain Fatty Acid Transport Protein FadL .......................................................................................458
Fatty Acyl-CoA Synthetase ...................................................................................................................................459
VECTORIAL ACYLATION: ONE MECHANISM OPERATIONAL IN FATTY ACID TRANSPORT...........460
THE BACTERIAL PARADIGM ...............................................................................................................................460
Energetics of Fatty Acid Transport in Gram-Negative Bacteria......................................................................460
The Fatty Acid Transporter FadL........................................................................................................................461
The Fatty Acyl-CoA Synthetase FadD..................................................................................................................461
Structural Considerations of FACS .....................................................................................................................462
FATTY ACID TRANSPORT AND ACTIVATION IN YEAST: EVIDENCE FOR A MULTICOMPONENT
COMPLEX..........................................................................................................................................................463
Role of Fat1p ..........................................................................................................................................................464
Directed Mutagenesis of FAT1 and Functional Organization of Fat1p..........................................................464
The Fatty Acyl-CoA Synthetases Faa1p and Faa4p...........................................................................................465
Interaction of Fat1p and FACS ............................................................................................................................465
FATTY ACID TRANSPORT AND BIOLOGICAL MEMBRANES .....................................................................466
Long-Chain Fatty Acid Transport and Activation in Bacteria: Implications in Early States of
Infection ..............................................................................................................................................................466
Fatty Acid Transport and Trafficking in Yeast ..................................................................................................468
Lessons Applied to Mammalian Systems............................................................................................................469
ACKNOWLEDGMENTS ..........................................................................................................................................469
REFERENCES ...........................................................................................................................................................469
Included in
Biochemistry Commons, Biotechnology Commons, Other Biochemistry, Biophysics, and Structural Biology Commons
Comments
Copyright © 2003, American Society for Microbiology. All Rights Reserved.