Tryptophane Metabolism X. The Effect Of Feeding 1(-)-, Dl-, And D(+)-Tryptophane, D(-)And Dl-(β-3-Indolelactic Acid,(β-3-Indolepyruvic Acid, And L(-)Kynurenine Upon The Storage Of Liver Glycogen And The Urinary Output Of Kynurenic Acid, Kynurenine, And Total Acetone Bodies

Authors

• Raymond Borchers, State University of Iowa
• Clarence P. Berg, State University of Iowa
• Newton E. Whitman, State University of Iowa

Document Type

Article

Date of this Version

1942

Citation

J. BioI. Chem. 1942 145: 657-666.

Comments

Copyright 1942 the authors.

Abstract

The amount of tryptophane required for maintenance and growth is small (2). When an excess is supplied to some animals, kynurenic acid is excreted (3) and, under certain conditions, kynurenine also (4). Although these are quantitatively the most important of the known metabolic products of tryptophane, the amounts excreted in extensive tests in the dog and rabbit have usually accounted for less than half, more often for less than a third, of the tryptophane administered (4-6).