Biochemistry, Department of
Vadim Gladyshev Publications
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Document Type
Article
Date of this Version
2004
Abstract
Development of bioinformatics tools provided researchers with the ability to identify full sets of trace element–containing proteins in organisms for which complete genomic sequences are available. Recently, independent bioinformatics methods were used to identify all, or almost all, genes encoding selenocysteine-containing proteins in human, mouse, and Drosophila genomes, characterizing entire selenoproteomes in these organisms. It also should be possible to search for entire sets of other trace element–associated proteins, such as metal-containing proteins, although methods for their identification are still in development.
Comments
Published in Annual Review of Nutrition 2004. 24:579–96; doi: 10.1146/annurev.nutr.24.012003.132241