Biological Sciences, School of
School of Biological Sciences: Faculty Publications
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Document Type
Article
Date of this Version
2010
Abstract
Farnesol interacts with Candida albicans as both a quorum-sensing molecule and toxic agent, but confusion abounds regarding which conditions promote these distinct responses. Farnesol sensitivity was measured when inoculum cell history and size, temperature, and growth media were altered. Parameters for farnesol tolerance/ sensitivity were defined, validating previous studies and identifying new variables, such as energy availability. This study clearly defines what farnesol concentrations are lethal to C. albicans, based on environmental conditions.
Comments
Published in ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, Feb. 2010, p. 940–942, Copyright 2010 American Society for Microbiology, Used by Permission