Papers in the Biological Sciences

 

Document Type

Article

Date of this Version

2016

Citation

Data in Brief 7 (2016) 1652-1657

Comments

© 2016 Published by Elsevier Inc. This is an open access article under the CC BY license.

Abstract

A Drosophila melanogaster genome-wide transcriptome dataset is

available for studies on temporal patterns of gene expression. Gene

expression was measured using two-dye color oligonucleotide arrays

derived from Version 2 of the Drosophila Genomics Resource Center.

A total of 15,158 oligonucleotide probes corresponded to a high

proportion of the coding genes in the genome. The source of the flies

was a highly genetically heterogeneous population maintained in an

overlapping generation population regime. This regime was

designed to maintain life history traits so that they were similar to

those found in natural populations. Flies collected for the cohorts

were obtained in a short period of time in a carefully controlled

manner before virgin females and males were allowed to mate.

Mated females were introduced into two large population cages in

unusually high numbers (approximately 12,000 per cage) for a

Drosophila laboratory longevity study. Samples were taken weekly

from each cohort for 11 weeks; only a small proportion of surviving

flies were present at the last two collection time points and thus

they were exceptionally old compared to those collected in early-tomidlife

samples. The data set is useful for studies of temporal patterns

of gene expression as flies age. The very large size of each

cohort, and relatively frequent incidence of temporal samples, allows

for a fine-scale study of gene expression from young to very old flies.

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