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Document Type

Article

Date of this Version

2012

Citation

Chembiochem. 2012 November 26; 13(17): 2510–2512.

Comments

Copyright 2012 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.

doi:10.1002/cbic.201200560

Abstract

The design of sensors to monitor the activity state of specific protein kinases is challenging due to the complexity of eukaryotic kinomes. Here we describe a peptide-based photaffinity probe that specifically labels the active conformation of the Abl tyrosine kinase.

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