Ca(II)-Calmodulin Regulation of Fungal Dimorphism in Ceratocystis ulmi

Authors

Ganapathy Muthukumar, University of Nebraska-Lincoln
Kenneth W. Nickerson, University of Nebraska-LincolnFollow

Date of this Version

July 1984

Comments

Published in JOURNAL OF BACTERIOLOGY, July 1984, p. 390-392 Vol. 159, No. 1. Copyright 1984, American Society for Microbiology. Used by permission.

Abstract

We have shown that Ca(II) ions, ethylene glycol-bis(β-aminoethyl ether)- N,N-tetraacetic acid, LaCl₃, and six known calmodulin inhibitors shift the yeast-mycelium dimorphic potential of Ceratocystis ulmi. Our data are consistent with the conclusions that Ca(II)-calmodulin interaction is necessary for mycelial growth in C. ulmi and that the absence of this interaction leads to the yeast phase.