Enzyme- Facilitated Transport and Separation of Organic Acids through Liquid Membranes

Authors

David C. Rethwisch, Depaertment of Chemical and Biochemical Engineering and biocatalysis research Group, University of Iowa, Iowa.
Anuradha Subramanian, Department of chemical Engineering,University of Nebraska Lincoln.Follow
Gao Yi, Department of Chemical and biomolecular Engineering and Biocatalysis Research Group, University of Iowa
Jonathan S. Dordick, Department of Chemical and biomolecular Engineering and Biocatalysis Research Group, University of Iowa

Date of this Version

January 1990

Comments

This article was published in Journal of American Chemical Society, 112, pp 1649 - 1650, 1990. © American Chemical Society. Please contact the publisher for the full published version. Please visit American Chemical Society Publications home page

Abstract

The selective separation of organic acids is important for the production of numerous biologially functional rnuleculcs, including amino acids, peptidcs, fats, and pharmaceuticals.' Enzyme, specificalty lipases and proteases, have been used to selectively separate a variety of organic acids; however, multiple steps are usually required,Vn additiun, carbonic anhydrase has been usd in a variety of Eiquid membranes for transport of CO2.) In the present study, we have coupled the selectiviey of enzymes with liquid membranes to provide a single-step method to scicctiveiy separate and purify organic acids.