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Recently, hybrid structures of microorganisms with inorganic nanoscale moieties have received great interest owing to their potential in fabricating electronic systems. The electronic properties of metal nanoparticles, as a result of the singleelectron transport of current, make them ideal materials for nanodevices. Concomitantly, the nanostructure of microorganisms such as bacteria, viruses,[3, 4] and yeast are attractive scaffolds for the templating of metal nanoparticles through the interactions of the former with surface charges and the affinity of certain metals for specific biological molecules.[2–7] However, the key challenges in building hybrid devices are 1) to pattern nanostructures without destroying the biological construct of the microorganism and 2) to achieve active integration of a biological response to the electrical transport in a nanoparticle device.