Chemical and Biomolecular Engineering, Department of

 

Date of this Version

1996

Document Type

Article

Citation

Patent Number: 5,589,604

Comments

Appl. No.: 247,484

Abstract

Recombinant protein C characterized by a high percentage of active protein can be obtained in the milk of transgenic mammals that incorporate DNAs according to the present invention. Transgenic mammals of the present invention are produced by introducing into developing embryos DNA that encodes protein C, such that the DNA is stably incorporated in the DNA of germ line cells of the mature mammals and inherited in normal, mendelian fashion.

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