Chemical and Biomolecular Engineering, Department of: Papers in Subdisciplines
Papers in Biochemical Engineering
Date of this Version
8-19-2000
Abstract
Fermentation strategies for recombinant protein production in Pichia pastoris have been investigated and are reviewed here. Characteristics of the expression system, such as phenotypes and carbon utilization, are summarized. Recently reported results such as growth model establishment, application of a methanol sensor, optimization of substrate feeding strategy, DOstat controller design, mixed feed technology, and perfusion and continuous culture are discussed in detail.
Comments
This paper was originally published in the Journal of "Biotechnol. Bioprocess Eng."2000, 5: 275-287.