SELF-ASSEMBLED HETEROLEPTIC CHIRAL LIGANDS, ASYMMETRIC CATALYST SYSTEMS AND METHODS

Authors

James M. Takacs, Lincoln, NEFollow

Document Type

Article

Date of this Version

2010

Citation

Patent No.: US 7,847,114 B2

Comments

Appl. No.: 11/316,358

Abstract

A method of synthesizing a heteroleptic, multiple metal containing metallocyclic catalyst, particularly Suited for asymmetric catalysis, comprising combining a plurality of plural functional group-containing, monodentate ligands of complementary chirality, said plural functional groups being tethered to each other by tethers in the presence of a scaffold structural metal Ms or derivative thereof, wherein at least one functional group on each ligand combines to ligate M to form a bidentate, M_s centered ligand scaffold containing the remaining functional groups and combining said bidentate ligand scaffold with a catalytic metal M_c or derivative thereof whereby the remaining functional groups combine to ligate M_c, thereby forming said catalyst.