The Use of Rhenium (VII) Oxide as a Catalyst for the Substution of Hemiacetals

Authors

Michael W. Richardson, University of Nebraska-LincolnFollow

Date of this Version

Fall 11-29-2012

Document Type

Article

Comments

A THESIS Presented to the Faculty of The Graduate College at the University of Nebraska In Partial Fulfillment of Requirements For the Degree of Master of Science, Major: Chemistry, Under the Supervision of Patrick H. Dussault. Lincoln, Nebraska: November, 2012

Copyright (c) 2012 Michael W. Richardson

Abstract

Rhenium (VII) oxides have proven to be mild and versatile catalysts in organic chemistry. They have previously been utilized to catalyze the transposition of allylic aclohols, Prins reaction, and reductive amination to name a few examples. This thesis reports the application of Re(VII) oxide in the substitution of hemi-acetals with a wide array of nucleophiles including oxo-, thio-, and peroxy-nucleophiles. These reactions proceed efficiently with rapid reaction times and high yields.

Adviser: Patrick H. Dussault