Liangcheng Du, Professor
Vice-Chair
Department of Chemistry
729 Hamilton Hall
University of Nebraska-Lincoln

lincoln, Nebraska 68588 United States
ldu3@unl.edu

Research Interests:
Biosynthetic mechanism and metabolic engineering of novel antifungal and anti-MRSA antibiotics from gliding gram-negative bacteria, mycotoxins and other bioactive natural products from plant pathogenic fungi and endophytes

Du Research Group: http://chemweb.unl.edu/ldu/

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2023

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Identification and Biosynthetic Study of the Siderophore Lysochelin in the Biocontrol Agent Lysobacter enzymogenes, Amanda Lynn Miller, Shanren Li, Catherine D. Eichhorn, Yongbiao Zheng, and Liangcheng Du

2020

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LeTetR Positively Regulates 3-Hydroxylation of the Antifungal HSAF and Its Analogs in Lysobacter enzymogenes OH11, Lingjun Yu, Vimmy Khetrapal, Fengquan Liu, and Liangcheng Du

2018

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Spermidine-Regulated Biosynthesis of Heat-Stable Antifungal Factor (HSAF) in Lysobacter enzymogenes OH11, Yuan CHen, Fengquan Liu, and Liangcheng Du

2017

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Unusual acylation of chloramphenicol in Lysobacter enzymogenes, a biocontrol agent with intrinsic resistance to multiple antibiotics, Wei Zhang, Justin Huffman, Shengying Li, Yuemao Shen, and Liangcheng Du

2016

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Tricarballylic ester formation during biosynthesis of fumonisin mycotoxins in Fusarium verticillioides, Yaoyao Li, Lili Lou, Ronald Cerny, Robert A.E. Butchko, Robert H. Proctor, Yuemao Shen, and Liangcheng Du

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A TonB-dependent receptor regulates antifungal HSAF biosynthesis in Lysobacter, Ruping Wang, Huiyong Xu, Liangcheng Du, Shan-Ho Chou, Hongxia Liu, Youzhou Liu, Fengquan Liu, and Guoliang Qian

2011

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Transformation of Fusarium verticillioides with a polyketide gene cluster isolated from a fungal endophyte activates the biosynthesis of fusaric acid, Yunxuan Xie, Wei Zhang, Yaoyao Li, Mingzi Wang, Ronald Cerny, Yue Shen, and Liangcheng Du

2008

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Fumonisin level in corn-based food and feed from Linxian County, a high-risk area for esophageal cancer in China, Jiansheng Wang, Ying Zhou, Wanbo Liu, Xiangcheng Zhu, Liangcheng Du, and Qiaomei Wang

2006

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Distinct Ceramide Synthases Regulate Polarized Growth in the Filamentous Fungus Aspergillus nidulansD, Shaojie Li, Liangcheng Du, Gary Yuen, and Steven D. Harris

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Supplemental Materials for "Distinct Ceramide Synthases Regulate Polarized Growth in the Filamentous Fungus Aspergillus nidulansD", Shaojie Li, Liangcheng Du, Gary Yuen, and Steven D. Harris

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Functional replacement of the ketosynthase domain of FUM1 for the biosynthesis of fumonisins, a group of fungal reduced polyketides, Xiangcheng Zhu, Fengan Yu, R. S. Bojja, K. Zaleta-Rivera, and Liangcheng Du

2005

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Developing a genetic system for functional manipulations of FUM1, a polyketide synthase gene for the biosynthesis of fumonisins in Fusarium verticillioides, Fengan Yu, Xiangcheng Zhu, and Liangcheng Du

2004

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Fum3p, a 2-Ketoglutarate-Dependent Dioxygenase Required for C-5 Hydroxylation of Fumonisins in Fusarium verticillioides, Yousong Ding, Ravi S. Bojja, and Liangcheng Du

2001

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CYP83B1 Is the Oxime-metabolizing Enzyme in the Glucosinolate Pathway in Arabidopsis, Carsten Horslev Hansen, Liangcheng Du, Peter Naur, Carl Erik Olsen, Kristian B. Axelsen, Alastair J. Hick, John A. Pickett, and Barbara Ann Halkier

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The biosynthetic gene cluster for the anticancer drug bleomycin from Streptomyces verticillus ATCC15003 as a model for hybrid peptide–polyketide natural product biosynthesis, B. Shen, Liangcheng Du, C. Sanchez, D. J. Edwards, M. Chen, and J. M. Murrell