Date of this Version
Published as Chapter 1 in Terry M. Phillips (ed.), Clinical Applications of Capillary Electrophoresis: Methods and Protocols, Methods in Molecular Biology, vol. 1972
The development and general applications of capillary electrophoresis (CE) in the field of clinical chemistry are discussed. It is shown how the early development of electrophoresis was closely linked to clinical testing. The rise of gel electrophoresis in clinical chemistry is described, as well as the eventual developments that lead to the creation and the use of modern CE. The general principles of CE are reviewed and the potential advantages of this method in clinical testing are examined. Finally, an overview is presented of several areas in which CE has been developed and is currently being explored for use with clinical samples.