College of Dentistry: Faculty Publications
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Document Type
Article
Date of this Version
2014
Citation
THE JOURNAL OF BIOLOGICAL CHEMISTRY VOL. 289, NO. 34, pp. 23745–23752
Abstract
Background: Mitotic progression is regulated by reversible protein phosphorylation involving kinases and phosphatases.
Results: Pnuts functions as a master regulator of mitosis by modulating PP1; Pnuts expression peaks in mitosis and is degraded at mitotic exit.
Conclusion: This study reveals the function and regulation of a new and essential mitotic regulator.
Significance: This study improves our understanding of M-phase regulation.
COinS
Comments
© 2014 by The American Society for Biochemistry and Molecular Biology, Inc.