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Some Aspects of Cardenolide Metabolism With Particular Reference to the Hepatic Microsomal Nadph-dependent Mixed-function Oxidase System

RONALD EVERETT TALCOTT, University of Nebraska - Lincoln

Abstract

Historical Preface. The recorded history of cardiac glycosides and their natural sources begins with the mention of squill in the Ebers Papyrus." The ancient Romans used squill con- coctions as diuretics, heart tonics, emetics, and rat poisons.1 The ancient Chinese used a preparation of dried toad skin, Ch'an S, which contains vasoconstrictive as well as cardio- active principles, to cure bleeding of the gums. Primitive tribes of this century use Strophanthus preparations as arrow poisons, as they probably did in antiquity."

Subject Area

Pharmacology

Recommended Citation

TALCOTT, RONALD EVERETT, "Some Aspects of Cardenolide Metabolism With Particular Reference to the Hepatic Microsomal Nadph-dependent Mixed-function Oxidase System" (1973). ETD collection for University of Nebraska-Lincoln. AAI7413024.
https://digitalcommons.unl.edu/dissertations/AAI7413024

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