Food Science and Technology Department


Date of this Version



Frontiers in Immunology | March 2019 | Volume 10 | Article 427


2019 Schaefer, Hettinga, Cullor, German and Henrick


“Peripheral blood samples were collected at the time of enrollment (week 0) and serum was stored at −80◦C until subsequent analysis. Participants were then randomized into two groups and provided with equal concentration and quantity of either dairy or soy supplement provided in powdered form in coded, single-serving bags. Both participants and researchers were blinded to the type of protein received. Participants were asked to consume two servings of protein powder (6 grams/packet) with 4 ounces of water or applesauce twice per day, with meals, for a total of 8 weeks. At week 4, participants were vaccinated with DTaP vaccine (Sanofi Pasteur Inc., Swiftwater PA). A 0.5-mL dose of Adacel R is formulated to contain 5 Lf of tetanus toxoid, 2.5 Lf of diphtheria toxoid, 8 μg of inactivated PT, 8 μg of FHA, and 2.5 μg of pertactin (69 kiloDalton outermembrane protein). Each 0.5-mL dose contains aluminum hydroxide as adjuvant (not more than 0.39mg aluminum by assay), 4.5mg of sodium chloride, ≤ 100 μg of residual formaldehyde, and ≤ 100 μg of polysorbate 80 (Tween 80). A second blood draw was obtained 4 weeks after vaccination (week 8) and serumcollected for DTaP antibody analysis. The design and participant progression through the study is presented in Figure 1.” The authors apologize for this error and state that this does not change the scientific conclusions of the article in any way. The original article has been updated.

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