Outbreak of H7N8 Low Pathogenic Avian Influenza in Commercial Turkeys with Spontaneous Mutation to Highly Pathogenic Avian Influenza

Authors

• Mary Lea Killian, U.S. Department of Agriculture (USDA), Ames, Iowa
• Mia Kim Torchetti, US Department of Agriculture, Ames, IowaFollow
• Nichole Hines, US Department of Agriculture, Ames, Iowa
• Sam Yingst, Purdue University
• Thomas J. Deliberto, USDA/APHIS/WS National Wildlife Research CenterFollow
• Dong-Hun Lee, USDA Agriculture Research Service, Southeast Poultry Research Laboratory, Athens

Document Type

Article

Date of this Version

2016

Citation

Genome Announc 4(3):e00457-16.

doi:10.1128/genomeA.00457-16

Comments

US government work

Abstract

Highly pathogenic avian influenza (HPAI) subtype H7N8 was detected in commercial turkeys in January 2016. Control zone surveillance discovered a progenitor low pathogenic avian influenza (LPAI) virus in surrounding turkey flocks. Data analysis supports a single LPAI virus introduction followed by spontaneous mutation to HPAI on a single premises.