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This study evidences the growth of research literature produced by AIIMS (All India Institute of Medical Sciences) for the period of 2007 to 2016. A total of 14410 records were retrieved from the Scopus database. Descriptive statistics for the research publication output revealed mean = 1441, Sd = 318.92, minimum = 1087, maximum = 2141 at 95.0% confidence level. The curve fitting methodology was used to fit the growth of research publication of AIIMS. R square value for exponential growth model is higher (0.908) than the linear growth model (0.849). Journals are identified as most preferred publication pattern (69.42%). The research output of top 20 department aggregates to 57.77% of total productivity. This study also identified the top 20 most preferred journals by the faculties of AIIMS and comparison was made with the previous study revealed Indian Journal of Pediatrics, Indian Journal of Medical Research, and Indian Pediatrics were the most preferred journals among the faculties. The observation of this study exhibits that AIIMS plays a vital role in reducing disease burden of India by means of quantitative and qualitative research publications.