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Research productivity of any university is a reflection of its status quo in terms of its position in Higher Education Institution (HEI) ranking framework. This Scientometric study is an attempt to highlight the key features of research productivity of Science Faculty of Rashtrasant Tukadoji Maharaj Nagpur University based on the data collected from Web of Science database over a period of 30 years from 1990 to 2019.This article studied the publication trend by analysis of the 2229 research records. The major objectives of this study were to evaluate the research output in terms of number and type of publications, prolific and productive author, most preferred publication, citation analysis and so on. The complete research output is 2229 with an Annual Growth Rate (AGR) of 6.23 % with 11.4 % of average citations per paper. The period from year 2004 to 2019 was highly productive block with year 2015 contributing highest 7.31 % of the total number of publications during the study period. Physics was found to the core subject in which high level of quantitative as well as qualitative research has been performed by Science Faculty of the university. This paper is an attempt to portray a scientometric profile of the one of the oldest and premier university of India which will be help to highlight appropriate measures required for enhancing the research benchmark of the university to a new high.