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The present study aims to analyse the research output performance on Herbal Drugs, Medicines and Vaccines. A total of 973 research articles published in Web of Science database were analysed to find out the performance of Herbal Medicines, Drugs and Vaccines developers from all over the world in terms of growth of Publications and Citations impact during the period 1989-2021. Global publication shares, prolific author in the field, high productive Institutions, Journals, are studied in this article. The top most cited countries are: USA with 64799 Citations for 288 (29.6%) Publications followed by People R China with 29264 Citations for 185 (19%) Publications, UK with 22700 Citations for 112 Publications, Germany with 11522 Citations for 65 publications. India recorded 11859 Citations for 61 publications. The most productive institutions were: University Exeter (29), Harvard University National University of Singapore, Chinese Academy of Science and so on. The most Cited Institutions are: Harvard University with 9428 Citations for 22 Publications followed by Beth Israel Deaconess Med Ctr with 6476 Citations for 10 Publications, University of Exeter with 5411 Citations for 29 Publications. The most cited Paper is “Eisenberg DM, Davis RB, Ettner SL, Appel S, Wilkey S, et al., Trends in alternative medicine use in the United States, 1990-1997 - Results of a follow-up national survey, JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION. 1998 NOV 11; 280 (18): 1569-1575” with 4562 Citations. The most Cited journals were: JOURNAL OF ETHNOPHARMACOLOGY topped the list with 17235 Citations for 101 Publications followed by JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION with 7614 Citations for 8 Publications, PHYTOTHERAPY RESEARCH with 4761 Citations for 21 Publications. It noted that researcher has given the preference to highly impact Journals for their publications.