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ABSTRACT The study aimed at identifying the types of e-databases available, perceptions towards the ease and extent of use, and usefulness of the adopted e-databases and identify the challenges associated with the use of adopted e-databases by the postgraduate students in the selected universities, in North- central, Nigeria. The study adopted descriptive survey design where set of questionnaires were used to collect data from 1726 postgraduate students across five universities in North-central, Nigeria. The study found that Internet facility, e-journals, e-books, science direct, AGORA, DOAJ and TEEAL are the major e-databases available and accessible in selected libraries. The e-databases used on daily basis are Internet, e-books and e-journal while EMERALD, HINARI, EBSCOHOST, OARE, JSTOR and TEEAL are mostly accessed on yearly basis. The study identified poor interregional networking and Internet connection, high cost of e-databases, epileptic power supply and insufficient fund to subscribe to them as major challenges with the use of adopted e-databases. We concluded that there is a significant relationship between the perceived ease of use and use of e-databases among postgraduate students in those university libraries; as well as between perceived usefulness and use of e-databases.