The Evolutionary Dynamics of Infectious Diseases on an Unstable Planet: Insights from Modeling the Stockholm Paradigm

Authors

Angie T. C. Souza, Universidade Federal do ParanáFollow
Sabrina B. L. Araujo, Universidade Federal do Paraná
Walter A. Boeger, Universidade Federal do Paraná

ORCID IDs

Souza https://orcid.org/0000-0003-0592-8070

Date of this Version

12-15-2022

Document Type

Article

Citation

MANTER: Journal of Parasite Biodiversity (December 12, 2022 number 25

doi: 10.32873/unl.dc.manter25

Comments

Copyright © 2022, Souza, Araujo, and Boeger

License: CC BY-NC-SA 4.0 International

Abstract

Emerging infectious diseases (EIDs) are, besides a question of food safety and public health, an ecological and evolutionary issue. The recognition of this condition combined with the accumulation of evidence that pathogens are not specialists in their original hosts evidences the need for understanding how the dynamics of interaction between pathogens and hosts occurs. The Stockholm Paradigm (SP) provides the theoretical fundaments to understand the dynamics of diseases and design proactive measures to avoid the emergence and reemergence of infectious diseases. In this review, we revisit the models that evaluate several aspects of the proposed dynamics of the SP, including the complexity nature of the elements that have been associated with this new framework for the evolution of associations. We integrate the results from these studies into a putative dynamic of infectious diseases, discuss subordinate elements of this dynamic, and provide suggestions on how to integrate these findings into the DAMA (Document, Assess, Monitor, Act) protocol.