Date of this Version
International Symposium to Commemorate the 90th Anniversary of the Discovery of Chagas Disease, April 11-16 1999, Rio de Janeiro, Brazil, pages 429-432
Participants: Alejandro Luquetti, Aluízio Prata, Alvaro Moncayo, Alvaro Romanha, Ana Jansen, Bianca Zingales, Carlos Morel, Carlos Ponce, Egler Chiari, Elisa Cupolillo, Elisa Ponce, Felipe Guhl, Hooman Momen, José Rodrigues Coura, Mario Steindel, Michael Miles, Michel Tibayrenc, Octavio Fernandes, Riva Oliveira, Rodrigo Zeledón, Sonia Andrade, Toby Barrett, Vanize Macêdo, Zigman Brener
During this symposium the standardization of the nomenclature of Trypanosoma cruzi strains was discussed, in a parallel session, with a view to facilitating the use and understanding of a common nomenclature that would serve not only taxonomists but the general community of researchers working with T. cruzi.
The diversity in the behavior and morphology of T. cruzi isolates was soon recognized after the discovery of Chagas disease. Since then a variety of biochemical and molecular techniques have revealed the great genetic diversity present in strains of this parasite. Different investigators have described this diversity by using various terms. Correlation between this diversity and the complex epidemiological and clinical manifestations of the disease has however been hindered by the lack of a common nomenclature.
Recent studies have indicated a convergence among investigators regarding the clustering of strains of T. cruzi, into two principal groups. This consensus, together with the report of a meeting on the standardization of methods for T. cruzi classification held in Panama (unpublished document TDR/EPICHA-TCC/85.3 Geneva, World Health Organization, 1985), form the basis of the recommendations outlined in this document.