Mechanical & Materials Engineering, Department of
Date of this Version
Spring 2016
Citation
[1] Tsubaki A. T., Lewis W. M., and Terry B. S., 2014. “Implantation and Carrier Mechanism for Long-Term Biosensing in the Small Intestine.”
[2] Xie, W.2, Kothari, V., Terry, B., “A Bio-inspired Attachment Mechanism for Long-term Adhesion to the Small Intestine,” Biomedical Microdevices, 2015, DOI: 10.1007/s10544-015-9972-7.
Abstract
Biosensors are a tool that is growing in usage and is sought out by doctors and patients alike for being a non-invasive method to monitor health. The data that can be collected from these sensors can be analyzed by doctors that are away from patients, or even by patients that do not have the ability to see a doctor. The purpose of this work is to design and test a biosensor capsule that can attach itself to the inner wall of the small intestine for a short period of time before exiting the body. This research project was a continuation from work done in previous years. After performing 3 in vitro and in vivo tests with pig model intestine, the biosensor was able to successfully suck tissue into the capsule each test. The sensor was only able to attach to the inner wall of the small intestine successfully in the in vitro tests, but none of the in vivo tests. In order for the capsule to effectively attach a sensor inside the small intestine, future research must be done in redesigning the tissue capturing mechanism so the sensor can attach onto live tissue.