Nutrition and Health Sciences, Department of


Date of this Version



Curr Dev Nutr. 2022 Jun; 6(Suppl 1): 339. Published online 2022 Jun 14.

doi: 10.1093/cdn/nzac053.080

PMCID: PMC9193758


Objectives: Dietary γ -glutamyl peptides (γ -GPs) found in dry edible beans exhibit biological activities (antioxidant, anti-inflammatory) with potential benefits against chronic metabolic disorders. γ -GPs are responsible for the desirable Kokumi flavor through allosteric activation of the Calcium Sensing Receptor (CaSR) present in multiple mammalian tissues. In this study, we investigated the metabolic effects of γ -glutamyl valine (γ -EV) in diabetic obese mice.

Conclusions: γ -EV improved the diabetic condition of db/db mice via modulation of glucose and lipid metabolism.