Plum supplementation and lipid profile: a systematic review and meta-analysis of randomised controlled trials

Authors

Moein Askarpour, Shiraz University of Medical Sciences
Hamid Ghalandari, Shiraz University of Medical Sciences
Leila Setayesh, University of Nebraska-LincolnFollow
Ehsan Ghaedi, Tehran University of Medical Sciences

Document Type

Article

Date of this Version

10-17-2022

Citation

Journal of Nutritional Science (2023), vol. 12, e6, page 1 of 10. doi:10.1017/jns.2022.101

Comments

Open access.

Abstract

Plums are abundant in bioactive compounds which have been associated with numerous health benefits. In the present study, we aimed at examining the impact of plum supplementation on lipid profile of individuals. Electronic bibliographical databases were searched for relevant randomised clinical trials. Articles meeting our eligibility criteria were included for data extraction and final analysis. Weighted mean difference (WMD) was estimated using a random-effect model. Of the total articles retrieved in the initial search, nine articles were found to be eligible to be included in the analysis. Our results show that plum supplementation significantly improves total cholesterols levels in the unhealthy individuals. Moreover, plum supplementation reduces the LDL-c levels in the pooled sample (WMD=−11⋅52 mg/dl; 95 %CI−21⋅93,−1⋅11,P =0⋅03, I²=98⋅7 %) and also in some of the subgroups of individuals (dried plum, unhealthy subjects, duration more than 8weeks).Moreover, it had a significant reducing effect onTClevels just in unhealthy subjects. Although plumsupplementation did not have any significant impact on serumlevels of TGnorHDL-c.Our results show that supplementationwith plums is potentially effective in reducing serumtotal cholesterol and LDL-c.