Curated and harmonized gut microbiome 16S rRNA amplicon data from dietary fiber intervention studies in humans

Authors

Cynthia I. Rodriguez, University of California
Ali Keshavarzian, Rush University Medical Center
Bruce R. Hamaker, Purdue University
Feitong Liu, China Research and Innovation Center
Genelle R. Lunken, BC Children’s Hospital Research Institute
Heather Rasmussen, University of Nebraska-Lincoln
Hongwei Zhou, Zhujiang Hospital, Southern Medical University
Julien Tap, 9Universite Paris-Saclay
Kelly S. Swanson, University of Illinois at Urbana-Champaign
Maria Ukhanova, University of Florida
Marion Leclerc, Universite Paris-Saclay, Pendulum therapeutics
Martin Gotteland, University of Chile
Paola Navarrete, University of Chile
Petia Kovatcheva-Datchary, University of Würzburg
Wendy J. Dahl, University of Florida
Jennifer B. H. Martiny, University of California

Document Type

Article

Date of this Version

6-2-2023

Citation

Scientific Data | (2023) 10:346 | https://doi.org/10.1038/s41597-023-02254-4

Comments

Open access.

Abstract

Next generation amplicon sequencing has created a plethora of data from human microbiomes. The accessibility to this scientific data and its corresponding metadata is important for its reuse, to allow for new discoveries, verification of published results, and serving as path for reproducibility. Dietary fiber consumption has been associated with a variety of health benefits that are thought to be mediated by gut microbiota. To enable direct comparisons of the response of the gut microbiome to fiber, we obtained 16S rRNA sequencing data and its corresponding metadata from 11 fiber intervention studies for a total of 2,368 samples. We provide curated and pre-processed genetic data and common metadata for comparison across the different studies.