Plant Pathology Department
Document Type
Article
Date of this Version
December 2001
Abstract
Filamentous fungi form multicellular hyphae that are partitioned by septa. In A. nidulans, septum formation requires the assembly of a septal band following the completion of mitosis. Recent observations show that this band is a dynamic structure composed of actin, a septin and a formin. In addition, assembly is dependent upon a conserved protein kinase cascade that regulates mitotic exit and septation in yeast. Hyphal differentiation may reflect the regulation of this cascade by cyclin-dependent kinase activity. In this review, the dynamics and regulation underlying the assembly of the septal band are discussed.
Comments
Published in Current Opinion in Microbiology 4:6, (December 1, 2001), pp. 736–739; doi:10.1016/S1369-5274(01)00276-4 Copyright © 2001 Elsevier Science Ltd. Used by permission. http://www.sciencedirect.com/science/journal/13695274