Plant Pathology, Department of

 

Department of Plant Pathology: Faculty Publications

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Document Type

Article

Date of this Version

December 2001

Comments

Published in Current Opinion in Microbiology 4:6, (December 1, 2001), pp. 736–739; doi:10.1016/S1369-5274(01)00276-4 Copyright © 2001 Elsevier Science Ltd. Used by permission. http://www.sciencedirect.com/science/journal/13695274

Abstract

Filamentous fungi form multicellular hyphae that are partitioned by septa. In A. nidulans, septum formation requires the assembly of a septal band following the completion of mitosis. Recent observations show that this band is a dynamic structure composed of actin, a septin and a formin. In addition, assembly is dependent upon a conserved protein kinase cascade that regulates mitotic exit and septation in yeast. Hyphal differentiation may reflect the regulation of this cascade by cyclin-dependent kinase activity. In this review, the dynamics and regulation underlying the assembly of the septal band are discussed.

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